Chronic liver diseases and liver cancer an update in 2015 masatoshi kudo the 12th japan korea liver symposium was held in osaka on july 5 2015 in conjunction with the 6th asia pacific primary liver cancer expert meeting nishida et al 1 evaluated the antiviral response of triple therapy using peg interferon ribavirin and simepre vir peg ifn rbv smv in the context of early reduc . In the absence of chronic liver disease liver cancer is rare however in people with an underlying liver disease liver cancer may be quite common the exact cause of liver cancer is not known but scientists have identified many risk factors that can make someone more likely to develop liver cancer among those with chronic liver disease men are more likely to develop liver cancer than are . Sometimes the cause of liver cancer is known such as with chronic hepatitis infections but sometimes liver cancer happens in people with no underlying diseases and its not clear what causes it risk factors factors that increase the risk of primary liver cancer include chronic infection with hbv or hcv chronic infection with the hepatitis b virus hbv or hepatitis c virus hcv . Specifically their liver diseases cover viral hepatitis b15 b19 malignant neoplasm of the liver c22 and liver cirrhosis and other liver diseases k70 k76 the total cost of liver disease is estimated to 5689 billion won in 2008 latest year in the paper they are divided into 1032 billion won for medical cost 1815 7 billion won for transportation cost 012 133 billion won
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